Foundation Formula® stands as our flagship product, meticulously developed to address a wide spectrum of tick-borne diseases. This formulation provides 1500 mg each of Polygonum cuspidatum (Japanese knotweed) and Uncaria tomentosa (Cat’s claw) per 4 capsules. This groundbreaking formulation is enriched with bioactive compounds found in Japanese Knotweed, namely resveratrol, emodin, and quercetin. These potent constituents have demonstrated remarkable abilities to fortify the immune system and counteract inflammation – pivotal factors in combating tick-borne infections. Additionally, the product boasts formidable antimicrobial properties, effectively targeting harmful pathogens.
Japanese knotweed showcases remarkable antibacterial prowess through the inhibition of the bacterial DNA primase enzyme, along with its anti-MRSA activity facilitated by emodin. Furthermore, it exhibits profound anti-inflammatory effects, adeptly modulating the cellular immune system and curtailing pro-inflammatory cytokine formation through emodin, resveratrol, and citreorosein. The product’s potent antioxidant capabilities effectively thwart lipid peroxidation, stimulate glutathione production, and combat spirochetal infections.
Beyond its immune benefits, Japanese Knotweed delivers cardioprotective advantages by thwarting myocardial injury through NADPH oxidase and NF-κB activity inhibition, while also augmenting endothelium-dependent relaxation via heightened nitric oxide release. Moreover, this remarkable botanical serves as an immunomodulant/immunostimulant, efficiently normalizing immune responses and elevating macrophage and natural killer cell activities, rendering it invaluable for managing inflammatory and autoimmune conditions. The neuroprotective properties of Japanese Knotweed, attributed to its ability to traverse the blood-brain barrier, provide shield against hypoxic-ischemic brain injury and beta-amyloid-induced neurotoxicity.
Complementing this robust blend, Cat’s Claw enhances the formula with its proficient anti-inflammatory effects via NF-kappa Beta inhibition and potent antioxidant activity that effectively curtails inducible nitric oxide synthase gene expression and cell death. This botanical adeptly combats spirochetal infections, most notably Borrelia burgdorferi, in all its morphological forms, spanning spirochetes, round bodies, and biofilm-like colonies.
Further extending its therapeutic potential, Cat’s Claw showcases cardioprotective virtues by imparting antiarrhythmic and negative chronotropic effects through the inhibition of multiple ion channels. Notably, it exhibits a hypotensive effect, contributing to the reduction of systolic and diastolic blood pressures.
Remarkably, Cat’s Claw serves as an immunostimulant, inducing the proliferation of myeloid progenitors and normal resting B and T cell lymphocytes, while augmenting interleukin (IL-1) and IL-6 levels in lipopolysaccharide-stimulated macrophages, and heightening natural killer cell CD57+ expression.
Foundation Formula® expertly harnesses the extraordinary therapeutic potential of Japanese Knotweed and Cat’s Claw, delivering a comprehensive and naturally derived approach to promote overall well-being and address a diverse range of health conditions. Prepare to elevate your health support to unparalleled heights with this remarkable Bioactive Phytoextracts for Health Support.
