G3M Modified Citrus Pectin Powder is a natural blocker of galectin-3 (Gal-3) activity, an aging and cellular health biomarker.
Research shows that healthy Gal-3 activity in the circulation supports healthy aging, cellular function, cardiovascular health and normal immune response.
G3M Modified Citrus Pectin is a clinically studied pectin extracted from the pith of citrus fruit peels and modified to a low molecular weight to increase its absorption into circulation to provide systemic benefits.‡
Transcript from Dr. Hinchey’s Video on modified citrus pectin’s supporting role as a dietary supplement in her natural treatment of Lyme disease patients.
I’m going to stop and talk a little bit about galectin 3. How many people here have heard of galectin three before? Okay, good.
Galectin three is an alarm in it is something that responds to an injury or an infection immediately.
It’s supposed to be short-lived and then it’s supposed to turn off.
When somebody has a chronic infection it stays activated and it causes a lot of problems.
If you look at the monomer which is like the single little bar with like a pac man at the end that is called the monomer. And when it becomes activated it forms these pentamers which are five of them linked together, and then they can form lattices.
This is an integral part of the biofilm that these infections use to evade the immune system. You can see the Ligand at the bottom binding into the carbohydrate recognition binding domain. And what happens is this when it binds LPS, this activates it into the pentamer and into the lattice formation.
Galectin three is produced by the macrophages and other myeloid tissues and response to injury and infection. And it’s up-regulated by candida and several other bacteria, including a Herxheimer reaction.
This picture here you can see all of the different places where galectin three actually wreaks havoc on the digestive tract and really increases some of these cytokine cascades degrades the tight junctions and increases gut permeability.
Galectin three promotes immune suppression in chronic inflammatory conditions by forming these cross-links it suppresses immune surveillance It blocks the T cell receptor. It downregulates T cell signaling and it inhibits dendritic T-cell and natural killer cell function.
There is a natural inhibitor of galectin three which is modified citrus pectin.
Modified citrus pectin is from the pith of citrus and it’s been modified to a lower molecular weight and esterified to enhance GI absorption.
You can see the modified citrus pectin are these little…yellow squares. And they actually have a stronger binding affinity to the carbohydrate recognition domain than the LPS does So when the presence of modified citrus pectin, it will actually inject the LPS and it will bust up these pentamers.
And it can actually help to break down the biofilm.
There are several studies that I’m going to go through quickly regarding modified citrus pectin.
This first one is an in vitro study of cultured micro glial cells treated with LPS. And in the group that was given modified citrus pectin you can see a substantially lower amount of interleukin one beta. As well as interleukin six.
Modified citrus pectin protects against collagen breakdown.
It’s actually been shown to pull fibrosis out of tissues that are made of collagen and to promote healthy collagen production.
It helps to decrease Herxheimer reactions by binding to the endotoxins.
This was an in vivo study following a nerve injury that showed, compared to a sham, decrease levels of galectin three.
And modified citrus pectin also induces natural killer cell activity in a dose dependent relationship.
Modified citrus pectin binds heavy metals and toxins specifically lead, mercury and cadmium.
And modified citrus pectin really supports all five of my goals and treatment which is why I put almost every single patient on modified citrus pectin.
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What is Modified Citrus Pectin (MCP)?
Modified citrus pectin (MCP) is a form of pectin, a type of soluble fiber found in the cell walls of plants. It is derived from citrus peels and is modified through a process that makes it easier for the body to digest and absorb. Modified citrus pectin is often taken as a dietary supplement because it is thought to have various health benefits, such as supporting healthy cholesterol levels and promoting overall cardiovascular health. It is also sometimes used as a complementary or alternative treatment for cancer and other health conditions. ‡
Modified citrus pectin (MCP) & Lyme Disease
There is some evidence to suggest that modified citrus pectin may have potential as a complementary treatment for Lyme disease, a bacterial infection transmitted by ticks.‡
A few small studies have suggested that modified citrus pectin may help to reduce symptoms of Lyme disease and improve quality of life in people with the condition.‡
If you have been diagnosed with Lyme disease and are considering using modified citrus pectin or any other complementary or alternative treatment, it is important to discuss this with your healthcare provider. They can help you to determine the best course of treatment for your individual needs and circumstances.
Some of the potential benefits of modified citrus pectin (MCP) include:
- Supporting the health of the gut: Modified Citrus Pectin (MCP) may help to promote the growth of beneficial bacteria in the gut and reduce the growth of harmful bacteria.‡
- Reducing inflammation: Modified Citrus Pectin (MCP) may have anti-inflammatory properties that may help to reduce inflammation in the body.‡
- Supporting the immune system: Modified Citrus Pectin (MCP) may help to support the immune system by increasing the production of white blood cells.‡
- Lowering cholesterol levels: Modified Citrus Pectin (MCP) may help to lower cholesterol levels by binding to bile acids in the gut and promoting their excretion.‡
- Supporting cancer treatment: Some studies have suggested that Modified Citrus Pectin (MCP) may help to slow the growth of cancer cells and improve the effectiveness of certain cancer treatments.‡*It is important to note that more research is needed to confirm the benefits of MCP and to determine the most effective dosage. Also, it is always important to consult with a healthcare professional before taking any dietary supplement.